Paul Wellstone : The Plot Thickens

Hemolysis-associated hypercoagulability in sickle cell disease: the plot (and blood) thickens!

Peginterferon maintenance therapy in patients with advanced hepatitis C to prevent hepatocellular carcinoma: the plot thickens.

Skeletal Muscle Cells Generated from Pluripotent Stem Cells

Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-8502, Japan Stem Cell Institute, Paul and Sheila Wellstone Muscular Dystrophy Center, Department of Neurology, University of Minnesota Medical School, Minneapolis, MN 55455, USA Department of Comparative Biosciences, Stem Cell and Regenerative Medicine Center, University o...

MACHOs: THE PLOT THICKENS

We discuss the implications of the recent upward revision of the LMC microlensing rate by the MACHO Collaboration. We conclude: (i) A good case for the existence of baryonic dark matter in the halo has been made; (ii) The case for the existence of cold dark matter is unaffected and still compelling; and (iii) The Galactic halo is still an excellent place to search for cold dark matter particles...

FV and APC resistance: the plot thickens.

In this issue of Blood, Nogami et al report on a novel factor V (FV) gene mutation (FV Trp1920→Arg, FVNara) associated with activated protein C (APC) resistance and a severe thrombotic phenotype in a young Japanese patient. Since the affected amino acid residue is located in the light chain of FV, far from the known APC-cleavage sites, this discovery may afford new insights into the molecular m...